The primary difference between professional liability and commercial general liability (CGL) insurance is the type of risks they cover. CGL covers the cost of legal and medical expenses associated with claims alleging third-party property damage or bodily injury as a result of your business operations. Professional liability insurance also referred to as errors and omissions, provides coverage for claims alleging negligence or failure to deliver a professional service as promised, which may have led to a financial loss on your client’s behalf.